International Working Group of the Diabetic Foot – Guidelines: Neue Versionen der Leitlinien wurden auf dem “International Symposium on the Diabetic Foot” im Mai 2023 vorgestellt:

2023 Guidelines on Interventions to Enhance Healing of Foot Ulcers in People with Diabetes:

In these newly released guidelines, topical oxygen therapy was awarded a positive adjunctive treatment recommendation, consistent with the “A” grade recommendation previously awarded by the American Diabetes Association (ADA) in their Standards of Care in Diabetes 2023

  • Stand 2019 enthielten die “Wound healing interventions” Guidelines noch folgende Empfehlung:

We suggest not using topical oxygen therapy as a primary or adjunctive intervention in diabetic foot ulcers including those that are difficult to heal. (Weak; Low)

Studien, Literatur

Prospektive, nicht randomisierte Fallserie.

Conclusion: While these data are from a single-center and are single-armed, they represent the largest reported series of this therapy. This home-based therapy does show promise and warrants further investigation.


Rezeption in Deutschland

Gesundheitsökonomie, Versorgung

Cost-effectiveness is another major factor which has not been considered in this study. In the developing countries of Asia and Africa, this can be a game changer over which treatment method is preferred considering the fact that this study doesn’t prove any of the method to be superior. Studies have focussed on the high costs involved in VAC and its inability to be used on a regular basis in countries where the poor socioeconomic status of the patient makes it difficult (12). Though numerous studies have been conducted which use low cost VAC devices, large scale multicentric prospective studies are lacking regarding its efficacy (13). TOT in comparison to VAC, is cost effective considering the components which are required for its use(14,15). A sterile sealant, like a C arm cover, as well as continuous oxygen supply are ubiquitous in any hospital catering to orthopaedic and plastic surgery patients. Cost benefit studies are planned to be conducted in a full-fledged manner on the basis of the results of this pilot study.

Chan BC, Campbell KE. An economic evaluation examining the cost-effectiveness of continuous diffusion of oxygen therapy for individuals with diabetic foot ulcers. Int Wound J. 2020 Dec;17(6):1791-1808. doi: 10.1111/iwj.13468. Epub 2020 Jul 27. PMID: 33189100; PMCID: PMC7754389.

Sonstige Literatur

Abgrenzung hyperbare Sauerstofftherapie

Gemeinsamer Bundesausschuss

WebLinks, Sonstiges

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